Cara kalkulasi : Kalikan nilai Kei/Odds dengan team yang anda taruhkan dengan jumlah taruhan, lalu dikurangi jumlah taruhan anda.

There is absolutely no proof to recommend that Glu-131 performs any role in catalysis other than to help you coordinate the single divalent cation. The enzyme is level constrained with the cleavage in the amide bond.

m with compound one is because of the protonation on the phosphate moiety to the mono-anion. It's also curious to note which the ionization that's noticed at superior pH while in the log k

While the development is often the same, Naga Siren and her illusions have a random place while in the formation and possess all precisely the same dealing with angle.

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s are Shesha (or Ananta), who inside the Hindu myth of generation supports Narayana (Vishnu) as he lies on the cosmic ocean and on whom the established globe rests; Vasuki, who was utilized for a churning rope to churn the cosmic ocean of milk; and Takshaka, the tribal Main from the snakes.

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In November 2022, the Thai federal government declared the Naga as being the national symbol of Thailand, Using the goal of endorsing Thai tradition and traditions and growing the nation's cultural funds to push the Innovative economic system. The Naga is usually a legendary creature with very long-standing beliefs and connections for the Thai folks, and its designation as a countrywide image is an important stage toward preserving and promoting Thai tradition.

The structures from the compounds examined as substrates for NagA are introduced in Scheme six. The substitution of sulfur for oxygen can be utilized at the side of challenging and soft metals to probe the opportunity for metal-ligand conversation over the activation of electrophilic reactions (24, 25).

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there are actually tyrosine (Y223) and lysine (K139) residues that may additionally be contributing to your interaction While using the phosphate moiety with the substrate. Deprotonation of possibly of these residues at significant pH could cause a drop in the value of k

For that thio-amide substrates, the Cd-enzyme was the very best enzyme as well as Zn-enzyme was poorer. The catalytic constants for your Zn- and Cd-substituted types of NagA aid the conclusion that the carbonyl group of the substrate is polarized by a direct conversation with The only divalent cation certain to the Mβ-place within the active web site.